The quest thread Thiollier in Elden Ring: Shadow of the Erdtree it is not overly complicated to complete. Moving forward can be a pain, but following the mission itself is very easy… until you reach a very specific point where FromSoftware gets a little naughty. I’ll tell you how to solve the puzzle without spoilers about the story.
First you must meet Thiollier, aka the Lord of Poisons, along with the Grace called Cross of the Path of the Column in the Plain of Graves, south of Ensis Castle. Just make the introductions and exhaust all the dialogues. Then you must advance through the Shadow Realm until you see the message “A Great Rune has been broken” and head to At the Fissure in the southernmost area of the entire map.
Proceed through The Rift until you reach the final boss and defeat him. At the back of the fighting arena you will see a cave with a plant-human being. He offers you two options: Drink the nectar or Leave. Drink without fear and die. Common sense will tell you not to drink any more, but I tell you to repeat the action up to seven or eight more times.
Then visit Thiollier, tell him everything you have seen and return to the cave. She talks until she runs out of dialogue, drinks again, and repeats until she finishes the quest thread. I don’t need to tell you where you end the thread, because Fire Ring makes it very clear. When in doubt, he tries to drink a few more times just in case.
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